Hypothalamic Lin28a shows role in glucose homeostasis
(HealthDay)—An experimental study supports a TANK-binding kinase 1 (TBK-1)-dependent role for Lin28a in the hypothalamic ventromedial nucleus in glucose homeostasis. The study was published online May...
View ArticleClinical efficacy and future development of continuous glucose monitoring...
A growing body of data from clinical studies of continuous glucose monitoring (CGM) in type 1 diabetes supports the value of CGM for reducing variability in blood glucose levels and the risks of both...
View ArticleMindfulness-based therapy may reduce stress in overweight and obese individuals
In a randomized clinical trial of women who were overweight or obese, mindfulness-based stress reduction (MBSR) increased mindfulness and decreased stress compared with health education. In addition,...
View ArticleInsulin release is controlled by the amount of Epac2A at the secretory vesicles
Specialized beta cells in the pancreas release the hormone insulin to control our blood glucose levels, and failure of this mechanism is central to the development of type-2 diabetes. How much and when...
View ArticleFirst-generation 'artificial pancreas' brings hope for people with type 1...
A new "artificial pancreas" being studied by the University of Melbourne could dramatically transform the lives of people with type 1 diabetes.
View ArticleAlzheimer's drug cuts hallmark inflammation related to metabolic syndrome by...
An existing Alzheimer's medication slashes inflammation and insulin resistance in patients with metabolic syndrome, a potential therapeutic intervention for a highly dangerous condition affecting 30...
View ArticleScreen time linked to diabetes
Daily screen time of three or more hours is linked to several risk factors associated with the development of diabetes in children, according to a study by St George's, University of London.
View ArticleTransforming skin cells to insulin
Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers' aim is to transplant these...
View ArticleChildren who sleep an hour less at higher risk of type 2 diabetes, says study
A study has found that children who slept on average one hour less a night had higher risk factors for type 2 diabetes, including higher levels of blood glucose and insulin resistance.
View ArticleSubstance in coffee delays onset of diabetes in laboratory mice
In recent years, researchers have identified substances in coffee that could help quash the risk of developing Type 2 diabetes. But few of these have been tested in animals. Now in study appearing in...
View ArticleSix meals per day is better than three for blood sugar control in obese...
Six meals per day is better than three for blood sugar control in obese people with impaired glucose tolerance (prediabetes) or full-blown type 2 diabetes, suggests new research presented at this...
View ArticleDrug for type 2 diabetes provides significant benefits to type 1 diabetic...
A majority of patients with Type 1 diabetes who were treated with dapagliflozin, a Type 2 diabetes medicine, had a significant decline in their blood sugar levels, according to a new study published in...
View ArticleInsulin therapy initially declined and delayed by an average of two years
Although delaying insulin therapy leads to a worsening progression of diabetes, new research by Brigham and Women's Hospital has found 30 percent of type 2 diabetic patients don't begin insulin, a...
View ArticleAbbott wins FDA approval for diabetes device that doesn't require routine...
Abbott Laboratories has gained clearance to start selling in the U.S. the first continuous glucose monitor that does not require people with diabetes to routinely prick their fingers.
View ArticleInsulin signaling molecule in liver controls levels of triglyceride in blood
A new animal study shows how insulin controls the movement and storage of fat molecules in the liver and how a breakdown in this system could lead to non-alcoholic fatty liver disease and changes in...
View ArticleDiabetes: New insulin sensitizers discovered
A root cause of type 2 diabetes is a condition known as insulin resistance, in which cells stop responding to commands from the hormone that regulates glucose (sugar) storage. Restoring insulin...
View ArticleTofogliflozin most effective with high baseline insulin
(HealthDay)—The sodium glucose co-transporter 2 inhibitor tofogliflozin is effective for reducing fasting plasma glucose and body weight, particularly in patients with a high insulin level at baseline,...
View ArticleResearchers design synthetic beta cells to secrete insulin in response to...
Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the...
View ArticleYour bones affect your appetite—and your metabolism
Your skeleton is much more than the structure supporting your muscles and other tissues. It produces hormones, too. And Mathieu Ferron knows a lot about it. The researcher at the Montreal Clinical...
View ArticleSimplified method allows CGM users to leverage trend arrow data
Endocrine Society experts have developed a streamlined method for using the Dexcom G5 Mobile Continuous Glucose Monitor (CGM) to help individuals with diabetes maintain better control of their glucose...
View ArticleCritical link between obesity and diabetes has been identified
UT Southwestern researchers have identified a major mechanism by which obesity causes type 2 diabetes, which is a common complication of being overweight that afflicts more than 30 million Americans...
View ArticleGene therapy restores normal blood glucose levels in mice with type 1 diabetes
Type 1 diabetes is a chronic disease in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in high blood levels of glucose. A study published January...
View ArticleBig strides made in diabetes care
(HealthDay)—This past year was a busy, productive one for diabetes research and care.
View ArticleArsenic-tainted drinking water may increase diabetes risk
A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes. The paper, published ahead of print in the American...
View ArticleDiabetes gene found that causes low and high blood sugar levels in the same...
A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.
View ArticleSmart insulin patch may aid future therapies
A smart insulin patch, once translated for humans, could eliminate the need for constant blood testing and help diabetics maintain a more consistent level of blood glucose.
View ArticleBrain scans show why some type 1 diabetics miss low blood sugar cues
The brains of people with type 1 diabetes react differently to low blood sugar compared with healthy adults, say Yale researchers.
View ArticleAn experiment in mice palliates kidney disease caused by diabetes
Diabetes has become a major health problem worldwide; some estimates suggest that in 20 years, there will be around 600 million diabetics. The disease is caused by impaired insulin secretion, which in...
View ArticlePeptide improves glucose and insulin sensitivity, lowers weight in mice
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of...
View ArticleChemist designs diabetic treatment minus harmful side effects
A chemist in the College of Arts and Sciences (A&S) has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.
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